News Summary: Elephant zombie gene, Thalidomide mechanism revealed

A brief summary of a few recent news items of interest to cancer researchers

‘Zombie gene’ protects elephants from cancer

A newly described gene that was resurrected in elephants 59 million years ago, LIF6, may take part in protecting the animals from cancer. LIF is a very exciting new target, but it’s also hit the global headlines because zombies are cool. Read more / Read the study in Cell Reports

Plan to replicate 50 high-impact cancer papers shrinks to just 18

The Reproducibility Project: Cancer Biology is an ambitious project that began in 2013, aiming to replicate experiments from 50 high-impact cancer biology papers. After gradually reducing its target, it now expects to complete just 18 studies. Read more

After 60 years, scientists uncover how thalidomide produced birth defects

Scientists at Dana-Farber Cancer Institute have uncovered the mechanism of how thalidomide produced birth defects. The study authors claim the finding will be critical as pharmaceutical companies develop a promising new generation of anticancer drugs that share a basic chemical architecture with thalidomide. Read press release / Read study in eLife

EACR member Thomas Helledey to move to University of Sheffield, UK

EACR member Professor Thomas Helledey is moving from the Karolinska Institutet in Sweden to the University of Sheffield, UK, as a Chair of Translational Oncology. Read more and watch a video of Professor Helledey talking about the move